Pharmacyclics
(NASDAQ: PCYC)
88.26
+1.07
+1.23%
+1.07
+1.23%
MORE ON PCYC
COMPANY INFORMATION
| Exchange: | NASDAQ national market |
| Stock: | Pharmacyclics, Inc. |
| Industry: | Drug Manufacturers - Specialty & Generic |
| Employees: | 224 |
DESCRIPTION
| Pharmacyclics, Inc. was incorporated in Delaware in 1991 and commenced operations in 1992. It is a clinical-stage biopharmaceutical company focused on developing and commercializing small-molecule drugs for the treatment of cancer and immune mediated diseases. The Company’s corporate mission statement reads as follows: To build a viable biopharmaceutical company that designs, develops and commercializes novel therapies intended to improve quality of life, increase duration of life and resolve serious medical healthcare needs; To identify promising product candidates based on exceptional scientific development expertise, develop its products in a cost-efficient manner and to pursue commercialization and/or development partners when and where appropriate. Presently, Pharmacyclics has three product candidates in clinical development and several preclinical molecules in lead optimization. The Company is committed to high standards of ethics, scientific rigor, and operational efficiency as it moves each of these programs toward potential commercialization. The Company’s clinical development and product candidates are small-molecule enzyme inhibitors designed to target key biochemical pathways involved in human diseases with critical unmet needs. It currently has three proprietary drug candidates under clinical development and several preclinical lead molecules. These include: an inhibitor of Bruton’s tyrosine kinase (BTK) ibrutinib (PCI-32765, hereafter referred to as ibrutinib) currently initiating Phase III studies in hematologic malignancies, a BTK inhibitor lead optimization program targeting anti-inflammatory and autoimmune indications, an inhibitor of Factor VIIa (PCI-27483) in a Phase II clinical trial in pancreatic cancer and a HDAC inhibitor abexinostat (formerly known as PCI-24781) currently in Phase I and II clinical trials in solid tumors and hematological malignancies. It uses third parties to manufacture various components of its products under development. The Company owns or controls granted patents in the U.S., Europe, Japan and Australia, that claim the ibrutinib compound and related BTK inhibitor compounds as compositions of matter. It faces intense competition for each of its drug targets from pharmaceutical companies, universities, governmental entities and others in the development of therapeutic and diagnostic agents for the treatment of diseases. It is subject to regulation by federal, state and other authorities within the United States and numerous entities outside of the United States. |
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