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|Nuvasive Inc, was incorporated in Delaware in July 1997. The Company is a medical device company engaged in developing minimally disruptive surgical products and procedures for the spine. The Company’s currently-marketed product portfolio is engaged in applications for spine fusion surgery, including biologics. The Company's main product offering includes a minimally disruptive surgical platform called Maximum Access Surgery, or MAS®, as well as an offering of biologics, cervical, motion preservation products, and Intra-Operative Monitoring (IOM) services. Its spine surgery product line offerings, which include products for the thoracolumbar spine, the cervical spine, and a set of motion preservation product offerings still under development, are mainly used to enable access to the spine and to perform restorative and fusion procedures in a minimally disruptive fashion. Its biologic product line offerings include allograft, (donated human tissue) — Triad ®, and Osteocel Plus®, an allograft cellular matrix containing viable mesenchymal stem cells, FormaGraft®, a collagen synthetic product used to aid the fusion process, and AttraX®, a synthetic bone graft material, which is still in the process of U.S. regulatory clearance, to aid in spinal fusion. Its MAS platform, with the unique advantages provided by its nerve monitoring systems, enables an innovative lateral procedure known as eXtreme Lateral Interbody Fusion, or XLIF®, in which surgeons access the spine for a fusion procedure from the side of the patient’s body, rather than from the front or back. Its MaXcess instruments provide access to the spine in a manner that affords direct visualization and its nerve monitoring systems allow surgeons to avoid critical nerves. Its cervical product offering now provides a full set of solutions for cervical fusion surgery, including allograft and CoRoent® implants, as well as cervical plating and posterior fixation products, and a set of motion preservation product offerings still under development. The Company competes with Medtronic Sofamor Danek (Medtronic), Natus, Cadwell Laboratories, and VIASYS Healthcare, a division of CareFusion Corporation DePuy, Stryker Spine and Synthes, Inc. The Company’s products,medical devices and tissues subject to regulation by the FDA and other regulatory bodies.|
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