11.75 Down -0.24 -2.00%
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OWNERSHIP INFORMATION
Shares Outstanding 67.00 Mil
Institutional Ownership (%) 85.07
Top 10 Institutions (%) 56.10
Mutual Fund Ownership (%) 0.54
5%/Insider Ownership (%) 2.40
Float (%) 97.60
OWNERSHIP ACTIVITY
DESCRIPTION # OF HOLDERS SHARES
Total Positions 124 56,995,254
New Positions 22 0
Soldout Positions 68 0
Net Position Change -38 -8,381,201
Buyers 66 7,170,842
Sellers 104 -15,552,043
VIEW:
INSTITUTION NAME SHS HELD SHS CHG %CHG $CHG* %OUT %PORT RPT DATE
Fidelity Management & Research Company 9,071,862 17,339 0.2 42,586,010 13.6 0 03-31-13
OrbiMed Advisors, LLC 5,207,600 764,700 17.2 30,091,524 7.8 1.6 03-31-13
T. Rowe Price Associates, Inc. 5,111,239 -63,400 -1.2 23,446,366 7.7 0 03-31-13
Perceptive Advisors LLC 4,402,637 310,500 7.6 22,926,881 6.6 7.1 03-31-13
BlackRock Institutional Trust Company, N.A. 3,903,769 269,937 7.4 20,288,768 5.9 0 03-31-13
The Vanguard Group, Inc. 2,297,233 -1,184,049 -34 1,894,364 3.4 0 03-31-13
Visium Asset Management, LP 2,283,917 -90,180 -3.8 10,014,185 3.4 0.9 03-31-13
VHCP Management, LLC 1,964,673 -257,273 -11.6 7,270,268 2.9 18.1 03-31-13
State Street Global Advisors (US) 1,768,514 211,971 13.6 9,862,188 2.7 0 03-31-13
Jennison Associates LLC 1,608,742 7,405 0.5 7,584,302 2.4 0 03-31-13
Loomis, Sayles & Company, L.P. 1,292,019 22,506 1.8 6,214,994 1.9 0.1 03-31-13
Turner Investment Partners, Inc. 1,291,308 1,182,058 1,082 14,885,115 1.9 0.2 03-31-13
Franklin Advisers, Inc. 1,081,400 58,500 5.7 5,498,532 1.6 0 03-31-13
Tekla Capital Management LLC 943,987 -538,662 -36.3 388,667 1.4 1.6 03-31-13
Wellington Management Company, LLP 934,453 -6,650 -0.7 4,323,498 1.4 0 03-31-13
  • *Category Headings:
  • Shs Held - shares held at report date
  • Shs Chg - position change within reporting period
  • %Chg - % change
  • $Chg - market value of the position change
  • %Out - % of shares outstanding
  • %Port - % Portfolio
  • Rpt Date - report date
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